Need help ASAP - Acronis Issues

[Docs IT]

I am trying to setup and run complete backup using the Acronis 2012 -see the following error codes

Failed to read data from the disk.
Failed to read from sector '746,230,560' of hard disk '1'.
Failed to read the snapshot. (0x10C45A)
CRC error (0x100155): ⎂Retry/⎂Ignore/Ignore ⎂All/⎂Cancel

More information about this error and solutions may be available online in the Acronis Knowledge Base.
To access the online resource manually, enter the event code at:
Event code: 0x000101F4

Is this error on the hard disk of the Toshiba PC or is the error on the backup Hard drive that was reformatted?

THANKS for the HELP !!!!!!