Depends on the hole. Hehe, that sounds funny....
Anyways...
Is it a brass insert embedded in the shell or threads on a hinge/mounting plate that are stripped?
If it's the brass inserts, not much you can do. If it's threading in a plate or hinge, you might be able to re-thread it with a tap & die set for instance. However, the hole would become bigger and you couldn't use the same screw.
Generally speaking, I don't bother repairing a stripped screw. If it's a broken brass insert, I'll glue one back in. If it's stripped though, and a critical holding point, I would recommend a new shell. If it's not a critical point, I'll just inform them of it so they are aware it's missing a screw and a little weaker.
If it's stripped on a plate or the hinge, that's a new hinge or plate.