And I can say the folks at eM Client testing take input from those who are using the beta and reporting things very seriously.
This client has a lot of potential for low-vision and blind clients if they can iron out the accessibility issues that still exist, and I've had several of the folks I know identifying those for them as they play with the beta. There's usually a response within a couple of hours to a day or two, at most, and each iteration of the beta has been addressing most of the issues identified.
It's been a refreshing experience, and one I've never experienced before.