After watching my single card rig run for 4 days now, I'd wager that it would be tough to cool dual cards in a regular OEM (in my case Dell Vostro) case. My GTX1060 runs at a pretty constant 72C, which is pretty hot. I can definitely feel that corner of the shop is warmer because of it. Also, for some reason earlier today, the temp spiked to 90C. I powered off the unit and let it cool down, then after finding nothing amiss mechanically, booted it back up again - it went right back to 72C - I hope that's not something I need to watch out for.
Anyway, if I were going to run dual cards in a single case, I'd make sure it was a full-sized tower and had some extra fans.