While I see the point of scanning a drive via USB on a faster machine, I typically would rather not "crack open" a machine to work on it if I don't have to. Reason? I can just see it now; drive was working but spyware-laced; I remove it, use a USB converter cable or enclosure, and wham-o, suddenly the HDD quits working. Now I've got a really PO'd customer who thinks that I caused their issue, when in reality, who knows what did it.
IMO, I feel better leaving a system intact, rather than playing with the guts inside of it. That's if I don't have to. Otherwise, if the machine isn't running or is on "life-support", then of course, I will open it for diagnosis. But messing with a hard drive that's working? I try to avoid it, if possible.